Part of my Clinical Sciences course included a focus on pharmacology; specifically, the importance of GPCR’s in drug treatment. G protein-coupled receptors, or GPCRs, are transmembrane receptors that receive an extracellular stimulus and activate a signal transduction pathway inside the cell. Almost half of all pharmaceutical drugs target GPCRs, as opposed to other membrane proteins, to enter cells. I chose to depict the GPCR Rhodopsin. Rhodopsin is a visual pigment in the retina responsible for vision in low-light conditions. Rhodopsin is composed of an opsin (7-transmembrane helices) covalently bound to a retinal (photoreactive chromophore). In my composition, Rhodopsin is the purple protein located within the phospholipid bilayer. Rhodopsin is activated by a photon of light which begins the signal transduction pathway, which I wont get into… Enjoy!